After discovering their goal touch on Saturday, Colne slipped to defeat on Wednesday night.
The Reds saw off an enterprising St Helens Town 4-0 at the XLCR Stadium on Saturday, before going down 1-0 at Silden in midweek.
Against St Helens, the visitors came close on the counterattack when Chad Whyte blasted a shot just over.
Tom Berwick’s shot whistled past the top corner, before Andy Tinker’s shot was deflected wide.
But again St Helens replied with a dangerous break and Andrew Gillespie fired into the side netting.
As half-time approached, a series of corners led to the breakthrough. Jason Hart’s inswinger saw Jonathan Hodgkinson out-jump the keeper and defenders and head home.
Early in the second half, Hart blasted a shot just over, and Chris Anderson saw his shot deflected wide.
As St Helens gave away a series of free kicks, it led to the second goal when Tom Berwick fired a 40-yard pile-driver into the net on 70 minutes.
Colne brought on Joe Garvin, and within a minute he found the net with a rocket of a shot on the turn from the edge of the area.
Danny Boyle’s tireless running earned him just reward after 83 minutes when he was brought down in the area and fired home the spot kick.
On Wednesday, Colne had the better of the early exchanges and good work by Adam Stockdale and Berwick resulted in Brandon Barski shooting just over.
But the hosts went in front when a goal kick led to a moment of hesitation in the Colne defence, and Hodgkinson’s clearance was charged down by Ben Crabtree, with Craig Nicholls calmly placed his shot beyond Chris Thompson.
Colne looked for an immediate response, and Berwick and Barski combined well on 22 minutes to release Tinker, who shot wide of the post.
The home keeper foiled further attempts by Berwick and Boyle before Berwick’s effort from 25 yards hit the top of the bar and went behind.
There was still time to see a fiercely driven effort by Barski whistle past the post before the break.
In the second half, Tinker headed over a Boyle corner,before substitute Garvin was inches away with a spectacular 30-yarder.
A series of half chances were spurned by the visitors before another excellent strike from Barski was well-saved.
Just after the hour, keeper Thorpe’s clearance was charged down by Barski, whose shot appeared to be cleared by a defender’s arm.
Colne appeals were in vain, and despite further chances for Tinker, Barski, Boyle, Garvin, Berwick and Hart, Silden held out.
The Reds are at Alsager Town tomorrow before hosting Barnoldswick Town on Tuesday night.